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منابع مشابه
Dmd056549 844..852
Oleanolic acid (OA) is a natural triterpenoid and has been demonstrated to protect against varieties of hepatotoxicants. Recently, however, OA at high doses was reported to produce apparent cholestasis in mice. In this study, we characterized the protective effect of OA at low doses against lithocholic acid (LCA)–induced cholestasis in mice and explored further mechanisms. OA cotreatment (5, 10...
متن کاملDmd058107 1334..1340
Anticancer agent 6-mercaptopurine (6MP) has been in use since 1953 for the treatment of childhood acute lymphoblastic leukemia (ALL) and inflammatory bowel disease. Despite being available for 60 years, several aspects of 6MP drug metabolism and pharmacokinetics in humans are unknown. Molybdoflavoenzymes such as aldehyde oxidase (AO) and xanthine oxidase (XO) have previously been implicated in ...
متن کاملPg 852-857 Tib
November 2005, Vol. 95, No. 11 SAMJ Uncertainty as to the cause or causes of sudden and unexpected infant death and difficulty in excluding the possibility of infanticide, even after the performance of a ‘complete’ autopsy, was graphically illustrated in the London courts recently. A mother wrongly convicted of killing her two sons had her conviction quashed, and the eminent paediatrician who h...
متن کامل726-735 Salim Mattar.pmd
Anaplasma and Ehrlichia species are important tick-borne pathogens that cause disease in cattle, dogs, horses and humans; with little information available about these agents in Colombia. The aim of this study was to provide molecular evidence for the presence of Anaplasma sp. and Ehrlichia sp. species in ticks collected from horses, dogs and cattle in Cordoba, Colombia. In this study, 1.105 ti...
متن کاملDmd049817 735..743
Paroxetine, a selective serotonin reuptake inhibitor, is metabolized in the liver and excreted into bile and urine as metabolites, but species differences have been observed in hepatic disposition between rats and humans. A major metabolite in rats is M1glucuronide, whereas M1-glucuronide and M1-sulfate are found in humans. The primary excretion route of paroxetine-derived radioactivity in rats...
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ژورنال
عنوان ژورنال: Ma?allat? Kulliyyat? Al-Ad?b Bi-Qin? (Print)
سال: 2021
ISSN: ['1110-709X', '1110-614X']
DOI: https://doi.org/10.21608/qarts.2021.54578.1025